Expresión de búsqueda: ALKB HOMOLOG 4, LYSINE DEMETHYLASE 
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Descriptor Inglés:   AlkB Homolog 4, Lysine Demethylase 
Descriptor Español:   Homólogo 4 de Alkb Lisina Desmetilasa 
Descriptor Portugués:   Homólogo AlkB 4 da Lisina Desmetilase 
Sinónimos Inglés:   Alkylated DNA Repair Protein AlkB Homolog 4
Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4
Alpha Ketoglutarate Dependent Dioxygenase Alkb Homolog 4  
Categoría:   D08.811.682.662.582.138
D08.811.682.690.416.139.937
Definición Inglés:   A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation. 
Nota Histórica Inglés:   2017 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   56501 
Identificador Único:   D000071501 

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